Isocyanide-based multi-component reactions for carrier-free and carrier-bound covalent immobilization of enzymes

Mehdi Mohammadi, Mansour Shahedi, Faezeh Ahrari, Mostafa Mostafavi, Zohreh Habibi, Maryam Yousefi

Published: 2023-02-28 DOI: 10.1038/s41596-023-00812-z

Isocyanide-based reactions

Enzyme immobilization

Covalent coupling

Multi-component reactions

Functional groups

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Strategies for the covalent immobilization of enzymes depend on the type of functional group selected to perform the coupling reaction, and on the relative importance of selectivity, loading capacity, immobilization time and activity/stability of the resu
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ACKNOWLEDGMENTS

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Isocyanide-based multi-component reactions for carrier-free and carrier-bound covalent immobilization of enzymes

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