The maternal serum metabolome by multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform and standardized data workflow for large-scale epidemiological studies

Meera Shanmuganathan, Zachary Kroezen, Biban Gill, Sandi Azab, Russell J. de Souza, Koon K. Teo, Stephanie Atkinson, Padmaja Subbarao, Dipika Desai, Sonia S. Anand, Philip Britz-McKibbin

Published: 2021-03-04 DOI: 10.1038/s41596-020-00475-0

mass spectrometry

serum metabolomics

capillary electrophoresis

standardized data workflow

large-scale epidemiological studies

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A standardized data workflow is described for large-scale serum metabolomic studies using multisegment injection-capillary electrophoresis-mass spectrometry. Multiplexed separations increase throughput (<4min/sample) for quantitative determinatio
Introduction
Materials
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ACKNOWLEDGMENTS

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The maternal serum metabolome by multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform and standardized data workflow for large-scale epidemiological studies

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